Dr. Mendelson is a graduate of Emory University and completed his neurology residency at Thomas Jefferson University in Philadelphia. He later went on to complete a fellowship in clinical neurophysiology at Emory University with a special concentration on the medical and surgical management of epilepsy.
Dr. Mendelson is board certified in neurology and clinical neurophysiology by the American Board of Psychiatry and Neurology.

He is the regional director of Neurology at Monmouth Medical Center and the director of the Epilepsy Monitoring Unit and stroke program at Monmouth Medical Center. He is active in medical education and is a Clinical Assistant Professor of Neurology at Drexel University College of Medicine.

He has special interests in the treatment of epilepsy during pregnancy and children with febrile seizures, and has authored book chapters on these subjects. He had extensive training at the Thomas Jefferson University Comprehensive Headache Center in the treatment of migraine and chronic daily headache.